It is known that adenomatous lesions can turn into cancer, which is mainly adenocarcinoma. And the canceration rate of ileocecal valve adenomatous lesion is not high. There is a research (4) that the ileocecal lesions were mainly benign, and small intestinal malignant tumors only accounted for 1-3% of all digestive tract malignant tumors, which is consistent with the results of this study. Enhancing colonoscopy screening is conducive to early detection of lesions and early treatment. We find that when the maximum diameter of the lesion is less than 0.6cm, the best endoscopic treatment is biopsy forceps. When the maximum diameter of the lesion is between 0.6cm and 2cm, the best endoscopic treatment is mainly EMR. When the maximum diameter of the lesion is≥2cm, the best endoscopic treatment is ESD, which is consistent with related literature report (5).